A randomised controlled trial of a strategy of switching to boosted protease inhibitor monotherapy versus continuing combination antiretroviral therapy for the long-term management of HIV-1 infected patients who have achieved sustained virological suppression on highly-active antiretroviral therapy.

PIVOT is a UK-based randomised clinical trial sponsored by the MRC CTU and funded by the HTA. A total of 587 HIV-positive patients have been recruited into the study which is currently in the follow-up phase which will last until November 2013.

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